Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation | bioRxiv
Molecular structure of an amyloid fibril formed by FUS low-complexity domain - ScienceDirect
A. Cartoon of FUS protein topology, showing the tyrosine rich low... | Download Scientific Diagram
Tuning levels of low-complexity domain interactions to modulate endogenous oncogenic transcription - ScienceDirect
Low-complexity domains adhere by reversible amyloid-like interactions between kinked β-sheets | bioRxiv
Imaging dynamic and selective low-complexity domain interactions that control gene transcription | Science
A) Schematic representation of a low complexity region-containing... | Download Scientific Diagram
Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains: Cell
The low-complexity domain of the FUS RNA binding protein self-assembles via the mutually exclusive use of two distinct cross-β cores | PNAS
Assessing the low complexity of protein sequences via the low complexity triangle | PLOS ONE
Sequence of HasCL10contig2, a repetitive low complexity domain (RLCD)... | Download Scientific Diagram
Imaging dynamic and selective low-complexity domain interactions that control gene transcription | Science
ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain - ScienceDirect
Sequence Determines the Switch in the Fibril Forming Regions in the Low- Complexity FUS Protein and Its Variants | The Journal of Physical Chemistry Letters
Phase separation of low-complexity domains in cellular function and disease | Experimental & Molecular Medicine
Low complexity and disordered regions of proteins have different structural and amino acid preferences - Molecular BioSystems (RSC Publishing) DOI:10.1039/C4MB00425F
Dissecting the role of low-complexity regions in the evolution of vertebrate proteins | BMC Ecology and Evolution | Full Text
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity | The EMBO Journal
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity | Nature Communications
Frontiers | Aberrant Phase Transitions: Side Effects and Novel Therapeutic Strategies in Human Disease
CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid | Nature Communications
Phase separation of low-complexity domains in cellular function and disease | Experimental & Molecular Medicine
Shasha Chong on Twitter: "(3/4) We also provide proof-of-concept demonstration that single-molecule measurements of protein diffusion rates can serve as an effective means for detecting phase separation in vivo. We detected a
